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Hepatocyte growth factor-like protein levels

DOCK3 · rs9869826

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 997 European ancestry individuals; replicated in 338 Greater Middle Eastern (Middle Eastern, North African or Persian), South Asian ancestry, Asian ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.542 lower (95% confidence interval 0.39-0.69); p = 2 × 10⁻¹².

Where it sits Chromosome 3, band 3p21.2 — in an intron of DOCK3.

What each result means

C/C Two copies of the version the research linked to Hepatocyte growth factor-like protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.

C/T One copy of the version the research linked to Hepatocyte growth factor-like protein levels. That is a smaller link than two copies.

T/T No copy of the version the research linked to Hepatocyte growth factor-like protein levels. This is the starting point the study compared everyone against.

Source

Connecting genetic risk to disease end points through the human blood plasma proteome

Suhre K, Arnold M, Bhagwat AM, Cotton RJ, Engelke R, Raffler J, Sarwath H, Thareja G, Wahl A, DeLisle RK, Gold L, Pezer M

and 12 more — show all

Lauc G, El-Din Selim MA, Mook-Kanamori DO, Al-Dous EK, Mohamoud YA, Malek J, Strauch K, Grallert H, Peters A, Kastenmüller G, Gieger C, Graumann J

Nature communications · 2017 · PMID 28240269 · open access

Questions about rs9869826

What is rs9869826?

rs9869826 is a single position in the genome, in or near the DOCK3 gene. Published research associates it with hepatocyte growth factor-like protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs9869826 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9869826 come from?

GWAS Catalog, Nature communications 2017, PMID:28240269. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Hepatocyte growth factor-like protein levels (rs9869826). MyGeneLog™. https://www.mygenelog.com/variants/rs9869826

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