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Who was studied 10,906 European ancestry cases, 366,221 European ancestry controls.
The effect
Each copy of the A allele carried 1.23 times the odds of Multiple myeloma (95% confidence interval 1.2-1.3); p = 2 × 10−20.
How common The A allele had a frequency of about 19% in the people studied.
Where it sits Chromosome 3, band 3p22.1 — between genes, 4.7 kb from GEMIN2P2.
What each result means
A/ATwo copies of the version the research linked to Multiple myeloma. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Multiple myeloma. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Multiple myeloma. This is the starting point the study compared everyone against.
Nature communications · 2024 · PMID 39103364 · open access
Questions about rs9856633
What is rs9856633?
rs9856633 is a single position in the genome, in or near the near GEMIN2P2 gene. Published research associates it with multiple myeloma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs9856633 linked to?
On MyGeneLog this position is linked to Multiple Myeloma. The research behind each link, and its sources, are set out on that condition page.
Does having rs9856633 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs9856633 come from?
GWAS Catalog, Nature communications 2024, PMID:39103364. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 102224Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others4Total10Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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