Sensitive

Diverticular disease

P2RY12 · rs9856118

Where this position leads

Condition: Diverticular Disease

rs9856118 Condition: Diverticular Disease Diverticular Disease Condition rs9856118 rs9856118 P2RY12

What the study found

Who was studied 27,444 British ancestry cases, 382,284 British ancestry controls.

The effect Each copy of the G allele shifted the measure 0.00467 lower; p = 9 × 10−11.

How common The G allele had a frequency of about 17% in the people studied.

Where it sits Chromosome 3, band 3q25.1 — in an intron of MED12L.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Diverticular disease — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Diverticular disease.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Diverticular disease compared to the general population.
Source

Questions about rs9856118

What is rs9856118?

rs9856118 is a single position in the genome, in or near the P2RY12 gene. Published research associates it with diverticular disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9856118 linked to?

On MyGeneLog this position is linked to Diverticular Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs9856118 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9856118 come from?

GWAS Catalog, Nat Genet 2018, PMID:30177863. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Diverticular disease (rs9856118). MyGeneLog™. https://www.mygenelog.com/variants/rs9856118

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