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CAD19 protein level (protein group normalized intensity)

near CDH19 · rs985088

What the study found

Who was studied 1,217 European, Hispanic or African ancestry individuals; replicated in 325 Arab, Indian or Filipino ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.43 lower (95% confidence interval 0.33-0.53); p = 3 × 10−17.

How common The C allele had a frequency of about 14% in the people studied.

Where it sits Chromosome 18, band 18q22.1 — between genes, 51.8 kb from CDH19.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of CAD19 protein level (protein group normalized intensity) compared to the general population.
C/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with CAD19 protein level (protein group normalized intensity).
G/G Published research associates this genotype with typical/baseline likelihood of CAD19 protein level (protein group normalized intensity) — no copies of the reported risk allele.
Source

Questions about rs985088

What is rs985088?

rs985088 is a single position in the genome, in or near the near CDH19 gene. Published research associates it with cad19 protein level (protein group normalized intensity). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs985088 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs985088 come from?

GWAS Catalog, Nature genetics 2025, PMID:41310232. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

CAD19 protein level (protein group normalized intensity) (rs985088). MyGeneLog™. https://www.mygenelog.com/variants/rs985088

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