SOX2-OT · rs9842371
Where this position leads
Condition: Cataract
What the study found
Who was studied 28,092 non-Hispanic White ancestry cases, 50,487 non-Hispanic White ancestry controls, 31,852 European ancestry cases, 428,084 European ancestry controls.
The effect The reported allele is T; the catalogue records no effect size ; p = 3 × 10−33.
Where it sits Chromosome 3, band 3q26.33 — in an intron of SOX2-OT.
rs9842371 is a single position in the genome, in or near the SOX2-OT gene. Published research associates it with cataracts. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Cataract. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Nature communications 2021, PMID:34127677. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Cataracts (rs9842371). MyGeneLog™. https://www.mygenelog.com/variants/rs9842371