Standard

Medication use (calcium channel blockers)

CACNA1D · rs9841978

Where this position leads

Condition: Medication Use as a Genetic Trait

rs9841978 Condition: Medication Use as a Genetic Trait Medication Use as a Genetic Trait Condition rs9841978 rs9841978 CACNA1D

What the study found

Who was studied 31,904 European ancestry cases, 172,474 European ancestry controls.

The effect Each copy of the A allele shifted the measure 0.0635 higher (95% confidence interval 0.047-0.08); p = 2 × 10−13.

How common The A allele had a frequency of about 32% in the people studied.

Where it sits Chromosome 3, band 3p21.1 — in an intron of CACNA1D.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Medication use (calcium channel blockers) compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Medication use (calcium channel blockers).
G/G Published research associates this genotype with typical/baseline likelihood of Medication use (calcium channel blockers) — no copies of the reported risk allele.
Source

Questions about rs9841978

What is rs9841978?

rs9841978 is a single position in the genome, in or near the CACNA1D gene. Published research associates it with medication use (calcium channel blockers). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9841978 linked to?

On MyGeneLog this position is linked to Medication Use as a Genetic Trait. The research behind each link, and its sources, are set out on that condition page.

Does having rs9841978 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9841978 come from?

GWAS Catalog, Nat Commun 2019, PMID:31015401. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Medication use (calcium channel blockers) (rs9841978). MyGeneLog™. https://www.mygenelog.com/variants/rs9841978

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