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Self-reported risk-taking behaviour

SOX2-OT · rs9841382

What the study found

Who was studied 113,882 European ancestry cases, 322,354 European ancestry controls.

The effect Each copy of the C allele carried 1.04 times the odds of Self-reported risk-taking behaviour (95% confidence interval 1.026-1.049); p = 7 × 10−11.

How common The C allele had a frequency of about 14% in the people studied.

Where it sits Chromosome 3, band 3q26.33 — in an intron of SOX2-OT.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Self-reported risk-taking behaviour compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Self-reported risk-taking behaviour.
T/T Published research associates this genotype with typical/baseline likelihood of Self-reported risk-taking behaviour — no copies of the reported risk allele.
Source

Questions about rs9841382

What is rs9841382?

rs9841382 is a single position in the genome, in or near the SOX2-OT gene. Published research associates it with self-reported risk-taking behaviour. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs9841382 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9841382 come from?

GWAS Catalog, Commun Biol 2018, PMID:30271922. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Self-reported risk-taking behaviour (rs9841382). MyGeneLog™. https://www.mygenelog.com/variants/rs9841382

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