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Who was studied 80,724 European ancestry cases, 748,975 European ancestry controls.
The effect
Each copy of the C allele carried 0.95 times the odds of Lumbar disc herniation (95% confidence interval 0.93-0.96); p = 2 × 10−16.
How common The C allele had a frequency of about 75% in the people studied.
Where it sits Chromosome 11, band 11p15.2 — in an intron of LINC02751.
What each result means
C/CPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Lumbar disc herniation compared to the general population.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Lumbar disc herniation.
T/TPublished research associates this genotype with typical/baseline likelihood of Lumbar disc herniation — no copies of the reported risk allele.
Nature communications · 2024 · PMID 39511132 · open access
Questions about rs9787942
What is rs9787942?
rs9787942 is a single position in the genome, in or near the LINC02751 gene. Published research associates it with lumbar disc herniation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs9787942 linked to?
On MyGeneLog this position is linked to Lumbar Disc Herniation. The research behind each link, and its sources, are set out on that condition page.
Does having rs9787942 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs9787942 come from?
GWAS Catalog, Nature communications 2024, PMID:39511132. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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