0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 35,035 East Asian ancestry cases, 35,771 East Asian ancestry controls, 5,958 Asian ancestry cases, 5,684 Asian ancestry controls.
The effect
Each copy of the T allele carried 1.10 times the odds of Breast cancer (95% confidence interval 1.06-1.13); p = 6 × 10−9.
How common The T allele had a frequency of about 22% in the people studied.
Where it sits Chromosome 9, band 9p21.3 — in an intron of CDKN2B-AS1.
What each result means
C/CNo copy of the version the research linked to Breast cancer. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Breast cancer. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Breast cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2020 · PMID 32139696 · open access
Questions about rs974336
What is rs974336?
rs974336 is a single position in the genome, in or near the CDKN2B-AS1 gene. Published research associates it with breast cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs974336 linked to?
On MyGeneLog this position is linked to Breast Cancer. The research behind each link, and its sources, are set out on that condition page.
Does having rs974336 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs974336 come from?
GWAS Catalog, Nature communications 2020, PMID:32139696. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Breast cancer (rs974336). MyGeneLog™. https://www.mygenelog.com/variants/rs974336