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TFPI protein levels

near F5 · rs970741

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.135 higher (95% confidence interval 0.12-0.15); p = 2 × 10−121.

How common The C allele had a frequency of about 27% in the people studied.

Where it sits Chromosome 1, band 1q24.2 — between genes, 1.1 kb from F5.

What each result means

C/C Two copies of the version the research linked to TFPI protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to TFPI protein levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to TFPI protein levels. This is the starting point the study compared everyone against.
Source

Questions about rs970741

What is rs970741?

rs970741 is a single position in the genome, in or near the near F5 gene. Published research associates it with tfpi protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs970741 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs970741 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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TFPI protein levels (rs970741). MyGeneLog™. https://www.mygenelog.com/variants/rs970741

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