Sensitive

Bipolar disorder or inflammatory bowel disease (MTAG)

ALOX5AP · rs9671125

Where this position leads

Condition: Inflammatory Bowel Disease

rs9671125 Condition: Inflammatory Bowel Disease Inflammatory Bowel Disease Condition rs9671125 rs9671125 ALOX5AP

What the study found

Who was studied 41,917 European ancestry bipolar disorder cases, 25,042 European ancestry inflammatory bowel disease cases, 406,464 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.012 higher (95% confidence interval 0.0081-0.0159); p = 1 × 10−8.

Where it sits Chromosome 13, band 13q12.3 — in an intron of ALOX5AP.

What each result means

G/G No copy of the version the research linked to Bipolar disorder or inflammatory bowel disease (MTAG). This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Bipolar disorder or inflammatory bowel disease (MTAG). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Bipolar disorder or inflammatory bowel disease (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs9671125

What is rs9671125?

rs9671125 is a single position in the genome, in or near the ALOX5AP gene. Published research associates it with bipolar disorder or inflammatory bowel disease (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9671125 linked to?

On MyGeneLog this position is linked to Inflammatory Bowel Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs9671125 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9671125 come from?

GWAS Catalog, Journal of affective disorders 2024, PMID:38154582. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Bipolar disorder or inflammatory bowel disease (MTAG) (rs9671125). MyGeneLog™. https://www.mygenelog.com/variants/rs9671125

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