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Takes medication for gout?

near KAT5 · rs9666878

Where this position leads

Condition: Gout

rs9666878 Condition: Gout Gout Condition rs9666878 rs9666878 near KAT5

What the study found

Who was studied 4,708 African American or Afro-Caribbean cases, 50,797 African American or Afro-Caribbean controls, 1,396 Hispanic or Latin American cases, 27,918 Hispanic or Latin American controls, 573 East Asian ancestry cases, 2,974 East Asian ancestry controls, 20,817 European ancestry cases, 294,851 European ancestry controls.

The effect Each copy of the C allele shifted the measure 0.0951 lower (95% confidence interval 0.077-0.113); p = 3 × 10−21.

How common The C allele had a frequency of about 66% in the people studied.

Where it sits Chromosome 11, band 11q13.1 — between genes, 3.7 kb from KAT5.

What each result means

A/A No copy of the version the research linked to Takes medication for gout?. This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Takes medication for gout?. That is a smaller link than two copies.
C/C Two copies of the version the research linked to Takes medication for gout?. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source
Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program
Verma A, Huffman JE, Rodriguez A, Conery M, Liu M, Ho YL, Kim Y, Heise DA, Guare L, Panickan VA, Garcon H, Linares F
and 59 more — show all
Costa L, Goethert I, Tipton R, Honerlaw J, Davies L, Whitbourne S, Cohen J, Posner DC, Sangar R, Murray M, Wang X, Dochtermann DR, Devineni P, Shi Y, Nandi TN, Assimes TL, Brunette CA, Carroll RJ, Clifford R, Duvall S, Gelernter J, Hung A, Iyengar SK, Joseph J, Kember R, Kranzler H, Kripke CM, Levey D, Luoh SW, Merritt VC, Overstreet C, Deak JD, Grant SFA, Polimanti R, Roussos P, Shakt G, Sun YV, Tsao N, Venkatesh S, Voloudakis G, Justice A, Begoli E, Ramoni R, Tourassi G, Pyarajan S, Tsao P, O'Donnell CJ, Muralidhar S, Moser J, Casas JP, Bick AG, Zhou W, Cai T, Voight BF, Cho K, Gaziano JM, Madduri RK, Damrauer S, Liao KP
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access

Questions about rs9666878

What is rs9666878?

rs9666878 is a single position in the genome, in or near the near KAT5 gene. Published research associates it with takes medication for gout?. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9666878 linked to?

On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.

Does having rs9666878 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9666878 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Takes medication for gout? (rs9666878). MyGeneLog™. https://www.mygenelog.com/variants/rs9666878

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