Sensitive

Prostate cancer

CASC8 · rs9656816

Where this position leads

Condition: Prostate Cancer

rs9656816 Condition: Prostate Cancer Prostate Cancer Condition rs9656816 rs9656816 CASC8

What the study found

Who was studied 2,738 Finnish ancestry cases, 2,400 Finnish ancestry controls.

The effect Each copy of the G allele shifted the measure 1.43 higher (95% confidence interval 1.28-1.60); p = 2 × 10−10.

How common The G allele had a frequency of about 12% in the people studied.

Where it sits Chromosome 8, band 8q24.21 — between genes, 40.3 kb from CASC8.

What each result means

A/A No copy of the version the research linked to Prostate cancer. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Prostate cancer. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Prostate cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs9656816

What is rs9656816?

rs9656816 is a single position in the genome, in or near the CASC8 gene. Published research associates it with prostate cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9656816 linked to?

On MyGeneLog this position is linked to Prostate Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs9656816 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9656816 come from?

GWAS Catalog, Prostate cancer and prostatic diseases 2021, PMID:34012061. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Prostate cancer (rs9656816). MyGeneLog™. https://www.mygenelog.com/variants/rs9656816

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