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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 289,782 European ancestry individuals; replicated in 5,165 European ancestry cases, 47,729 European ancestry controls.
The effect
Each copy of the A allele carried 1.01 times the odds of Preserved ratio impaired spirometry (95% confidence interval 1.004-1.008); p = 2 × 10−10.
How common The A allele had a frequency of about 75% in the people studied.
Where it sits Chromosome 7, band 7q21.11 — between genes, 18.4 kb from HMGN2P11.
What each result means
A/ATwo copies of the version the research linked to Preserved ratio impaired spirometry. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Preserved ratio impaired spirometry. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Preserved ratio impaired spirometry. This is the starting point the study compared everyone against.
The European respiratory journal · 2024 · PMID 38097206 · open access
Questions about rs9649071
What is rs9649071?
rs9649071 is a single position in the genome, in or near the near HMGN2P11 gene. Published research associates it with preserved ratio impaired spirometry. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs9649071 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs9649071 come from?
GWAS Catalog, The European respiratory journal 2024, PMID:38097206. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Preserved ratio impaired spirometry (rs9649071). MyGeneLog™. https://www.mygenelog.com/variants/rs9649071