Sensitive

Neuropsychiatric disorders

near OR5AZ1P · rs9645687

What the study found

Who was studied 19,099 European ancestry attention deficit hyperactivity disorder cases, 18,381 European ancestry autism spectrum disorder cases, 20,352 European ancestry bipolar disorder cases, 170,756 European ancestry major depressive disorder cases, 33,640 European ancestry schizophrenia cases, 466,420 European ancestry controls.

The effect Each copy of the T allele shifted the measure 5.79 z score lower; p = 7 × 10−9.

Where it sits Chromosome 11, band 11q12.1 — between genes, 8.5 kb from OR5AZ1P.

What each result means

C/C No copy of the version the research linked to Neuropsychiatric disorders. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Neuropsychiatric disorders. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Neuropsychiatric disorders. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs9645687

What is rs9645687?

rs9645687 is a single position in the genome, in or near the near OR5AZ1P gene. Published research associates it with neuropsychiatric disorders. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs9645687 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9645687 come from?

GWAS Catalog, Translational psychiatry 2021, PMID:33479212. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Neuropsychiatric disorders (rs9645687). MyGeneLog™. https://www.mygenelog.com/variants/rs9645687

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