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near EBF2 · rs9644102
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
Strength of the evidence
Its strongest genetic-study result is p = 10−9, with 1 associations in the GWAS Catalog.
4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10−50. 2: ClinVar from one lab (1 star), or p ≤ 10−20. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10−8). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.
What the study found
Who was studied 13,047 European ancestry cases, 262,499 European ancestry controls; replicated in 4,450 European ancestry cases, 87,398 European ancestry controls.
The effect The reported allele is T; the catalogue records no effect size ; p = 3 × 10−9.
How common The T allele had a frequency of about 74% in the people studied.
Where it sits Chromosome 8, band 8p21.2 — between genes, 128.8 kb from EBF2.
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Inguinal hernia (rs9644102). MyGeneLog™. https://www.mygenelog.com/variants/rs9644102