Standard

Ratio of omega-6 fatty acids to total fatty acids

near TBL2 · rs9638180

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0569 lower (95% confidence interval 0.047-0.067); p = 1 × 10⁻²⁷.

How common The A allele had a frequency of about 82% in the people studied.

Where it sits Chromosome 7, band 7q11.23 — between genes, 5.8 kb from TBL2.

What each result means

A/A Two copies of the version the research linked to Ratio of omega-6 fatty acids to total fatty acids. That is the strongest link of the three results. A link in a study is not a diagnosis.

A/G One copy of the version the research linked to Ratio of omega-6 fatty acids to total fatty acids. That is a smaller link than two copies.

G/G No copy of the version the research linked to Ratio of omega-6 fatty acids to total fatty acids. This is the starting point the study compared everyone against.

Source

Genome-wide characterization of circulating metabolic biomarkers

Karjalainen MK, Karthikeyan S, Oliver-Williams C, Sliz E, Allara E, Fung WT, Surendran P, Zhang W, Jousilahti P, Kristiansson K, Salomaa V, Goodwin M

and 75 more — show all

Hughes DA, Boehnke M, Fernandes Silva L, Yin X, Mahajan A, Neville MJ, van Zuydam NR, de Mutsert R, Li-Gao R, Mook-Kanamori DO, Demirkan A, Liu J, Noordam R, Trompet S, Chen Z, Kartsonaki C, Li L, Lin K, Hagenbeek FA, Hottenga JJ, Pool R, Ikram MA, van Meurs J, Haller T, Milaneschi Y, Kähönen M, Mishra PP, Joshi PK, Macdonald-Dunlop E, Mangino M, Zierer J, Acar IE, Hoyng CB, Lechanteur YTE, Franke L, Kurilshikov A, Zhernakova A, Beekman M, van den Akker EB, Kolcic I, Polasek O, Rudan I, Gieger C, Waldenberger M, Asselbergs FW, Hayward C, Fu J, den Hollander AI, Menni C, Spector TD, Wilson JF, Lehtimäki T, Raitakari OT, Penninx BWJH, Esko T, Walters RG, Jukema JW, Sattar N, Ghanbari M, Willems van Dijk K, Karpe F, McCarthy MI, Laakso M, Järvelin MR, Timpson NJ, Perola M, Kooner JS, Chambers JC, van Duijn C, Slagboom PE, Boomsma DI, Danesh J, Ala-Korpela M, Butterworth AS, Kettunen J

China Kadoorie Biobank Collaborative Group · Estonian Biobank Research Team · FinnGen

Nature · 2024 · PMID 38448586 · open access

Questions about rs9638180

What is rs9638180?

rs9638180 is a single position in the genome, in or near the near TBL2 gene. Published research associates it with ratio of omega-6 fatty acids to total fatty acids. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs9638180 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9638180 come from?

GWAS Catalog, Nature 2024, PMID:38448586. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Ratio of omega-6 fatty acids to total fatty acids (rs9638180). MyGeneLog™. https://www.mygenelog.com/variants/rs9638180

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