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Systolic blood pressure (MTAG)

GIT2 · rs9634314

Where this position leads

Condition: Blood Pressure

rs9634314 Condition: Blood Pressure Blood Pressure Condition rs9634314 rs9634314 GIT2

What the study found

Who was studied at least 757,601 European ancestry individuals (MTAG boosted by 455,258 Alzheimer's disease samples).

The effect Each copy of the A allele shifted the measure 0.0212 lower (95% confidence interval 0.015-0.027); p = 3 × 10−11.

Where it sits Chromosome 12, band 12q24.11 — in an intron of GIT2.

What each result means

A/A Two copies of the version the research linked to Systolic blood pressure (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Systolic blood pressure (MTAG). That is a smaller link than two copies.
G/G No copy of the version the research linked to Systolic blood pressure (MTAG). This is the starting point the study compared everyone against.
Source

Questions about rs9634314

What is rs9634314?

rs9634314 is a single position in the genome, in or near the GIT2 gene. Published research associates it with systolic blood pressure (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9634314 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs9634314 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9634314 come from?

GWAS Catalog, Nature communications 2024, PMID:39537608. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Systolic blood pressure (MTAG) (rs9634314). MyGeneLog™. https://www.mygenelog.com/variants/rs9634314

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