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Who was studied 1,823 European ancestry individuals; replicated in 1,836 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.349 lower (95% confidence interval 0.25-0.45); p = 9 × 10−13.
How common The T allele had a frequency of about 19% in the people studied.
Where it sits Chromosome 22, band 22q11.23 — in an intron of SMARCB1.
What each result means
C/CNo copy of the version the research linked to IgG glycosylation patterns. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to IgG glycosylation patterns. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to IgG glycosylation patterns. That is the strongest link of the three results. A link in a study is not a diagnosis.
Frontiers in immunology · 2018 · PMID 29535710 · open access
Questions about rs9624327
What is rs9624327?
rs9624327 is a single position in the genome, in or near the SMARCB1 gene. Published research associates it with igg glycosylation patterns. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs9624327 linked to?
On MyGeneLog this position is linked to IgG Glycosylation. The research behind each link, and its sources, are set out on that condition page.
Does having rs9624327 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs9624327 come from?
GWAS Catalog, Front Immunol 2018, PMID:29535710. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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