Sensitive

Breast cancer or hospitalized COVID-19 (pleiotropy)

TTC28 · rs9620778

Where this position leads

Condition: Breast Cancer

rs9620778 Condition: Breast Cancer Breast Cancer Condition rs9620778 rs9620778 TTC28

What the study found

Who was studied 133,384 European ancestry breast cancer cases, 32,519 European ancestry hospitalized COVID-19 cases, 2,176,594 European ancestry controls.

The effect The reported allele is A; the catalogue records no effect size ; p = 2 × 10−10.

Where it sits Chromosome 22, band 22q12.1 — in an intron of TTC28.

What each result means

A/A Two copies of the version the research linked to Breast cancer or hospitalized COVID-19 (pleiotropy). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Breast cancer or hospitalized COVID-19 (pleiotropy). That is a smaller link than two copies.
G/G No copy of the version the research linked to Breast cancer or hospitalized COVID-19 (pleiotropy). This is the starting point the study compared everyone against.
Source

Questions about rs9620778

What is rs9620778?

rs9620778 is a single position in the genome, in or near the TTC28 gene. Published research associates it with breast cancer or hospitalized covid-19 (pleiotropy). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9620778 linked to?

On MyGeneLog this position is linked to Breast Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs9620778 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9620778 come from?

GWAS Catalog, iScience 2023, PMID:37636041. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Breast cancer or hospitalized COVID-19 (pleiotropy) (rs9620778). MyGeneLog™. https://www.mygenelog.com/variants/rs9620778

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