Sensitive

Breast cancer

ZNRF3 · rs9613774

Where this position leads

Condition: Breast Cancer

rs9613774 Condition: Breast Cancer Breast Cancer Condition rs9613774 rs9613774 ZNRF3

What the study found

Who was studied 2,496 Taiwanese Han ancestry cases, 9,984 Taiwanese Han ancestry controls.

The effect Each copy of the G allele carried 0.70 times the odds of Breast cancer (95% confidence interval 0.65-0.74); p = 8 × 10−28.

How common The G allele had a frequency of about 36% in the people studied.

Where it sits Chromosome 22, band 22q12.1 — in an intron of ZNRF3.

What each result means

G/G Two copies of the version the research linked to Breast cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Breast cancer. That is a smaller link than two copies.
T/T No copy of the version the research linked to Breast cancer. This is the starting point the study compared everyone against.
Source

Questions about rs9613774

What is rs9613774?

rs9613774 is a single position in the genome, in or near the ZNRF3 gene. Published research associates it with breast cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9613774 linked to?

On MyGeneLog this position is linked to Breast Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs9613774 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9613774 come from?

GWAS Catalog, Breast cancer research and treatment 2024, PMID:37851288. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Breast cancer (rs9613774). MyGeneLog™. https://www.mygenelog.com/variants/rs9613774

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