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Chronotype

HES6PER2 · rs960783

What the study found

Who was studied 449,734 European ancestry individuals; replicated in 248,098 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.044 lower (95% confidence interval 0.036-0.052); p = 1 × 10−26.

How common The T allele had a frequency of about 4% in the people studied.

Where it sits Chromosome 2, band 2q37.3 — between genes, 0.3 kb from HES6.

What each result means

C/C No copy of the version the research linked to Chronotype. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Chronotype. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Chronotype. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs960783

What is rs960783?

rs960783 is a single position in the genome, in or near the HES6PER2 gene. Published research associates it with chronotype. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs960783 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs960783 come from?

GWAS Catalog, Nature communications 2019, PMID:30696823. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Chronotype (rs960783). MyGeneLog™. https://www.mygenelog.com/variants/rs960783

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