Sensitive

Alzheimer disease in low polygenic risk score (<50th percentile)

near BNIP3P1 · rs960000673

What the study found

Who was studied 2,232 European ancestry cases, 3,092 European ancestry controls.

The effect Each copy of the A allele carried 108.12 times the odds of Alzheimer disease in low polygenic risk score (<50th percentile) (95% confidence interval 22.0747922705217-529.547125537623); p = 8 × 10−9.

Where it sits Chromosome 14, band 14q12 — between genes, 96.7 kb from BNIP3P1.

What each result means

A/A Two copies of the version the research linked to Alzheimer disease in low polygenic risk score (<50th percentile). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Alzheimer disease in low polygenic risk score (<50th percentile). That is a smaller link than two copies.
C/C No copy of the version the research linked to Alzheimer disease in low polygenic risk score (<50th percentile). This is the starting point the study compared everyone against.
Source

Questions about rs960000673

What is rs960000673?

rs960000673 is a single position in the genome, in or near the near BNIP3P1 gene. Published research associates it with alzheimer disease in low polygenic risk score (<50th percentile). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs960000673 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs960000673 come from?

GWAS Catalog, Alzheimer's & dementia : the journal of the Alzheimer's Association 2026, PMID:42557982. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Alzheimer disease in low polygenic risk score (<50th percentile) (rs960000673). MyGeneLog™. https://www.mygenelog.com/variants/rs960000673

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