Standard

Cystatin C levels

DACH1 · rs9599885

Where this position leads

Condition: Gout

rs9599885 Condition: Gout Gout Condition rs9599885 rs9599885 DACH1

What the study found

Who was studied 342,399 European ancestry individuals, 6,015 African ancestry individuals, 7,338 South Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0255 lower (95% confidence interval 0.02-0.031); p = 2 × 10−22.

Where it sits Chromosome 13, band 13q21.33 — in an intron of DACH1.

What each result means

A/A Two copies of the version the research linked to Cystatin C levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Cystatin C levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Cystatin C levels. This is the starting point the study compared everyone against.
Source

Questions about rs9599885

What is rs9599885?

rs9599885 is a single position in the genome, in or near the DACH1 gene. Published research associates it with cystatin c levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9599885 linked to?

On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.

Does having rs9599885 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9599885 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Cystatin C levels (rs9599885). MyGeneLog™. https://www.mygenelog.com/variants/rs9599885

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