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Smoking initiation

near HMGN2P39 · rs9597900

What the study found

Who was studied 3,382,012 European ancestry, East Asian ancestry, Hispanic or Latin American, African ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0107 lower (95% confidence interval 0.009-0.0124); p = 3 × 10−36.

How common The G allele had a frequency of about 30% in the people studied.

Where it sits Chromosome 13, band 13q21.1 — between genes, 105.2 kb from HMGN2P39.

What each result means

A/A No copy of the version the research linked to Smoking initiation. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Smoking initiation. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Smoking initiation. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs9597900

What is rs9597900?

rs9597900 is a single position in the genome, in or near the near HMGN2P39 gene. Published research associates it with smoking initiation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs9597900 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9597900 come from?

GWAS Catalog, Nature 2022, PMID:36477530. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Smoking initiation (rs9597900). MyGeneLog™. https://www.mygenelog.com/variants/rs9597900

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