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Suicide attempts

GUCY1B2 · rs9596440

What the study found

Who was studied 1,271 Hispanics ancestry cases, 29,306 Hispanics ancestry controls.

The effect Each copy of the G allele carried 2.73 times the odds of Suicide attempts (95% confidence interval 2.38-3.08); p = 3 × 10−8.

Where it sits Chromosome 13, band 13q14.3 — in an intron of GUCY1B2.

What each result means

C/C No copy of the version the research linked to Suicide attempts. This is the starting point the study compared everyone against.
C/G One copy of the version the research linked to Suicide attempts. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Suicide attempts. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs9596440

What is rs9596440?

rs9596440 is a single position in the genome, in or near the GUCY1B2 gene. Published research associates it with suicide attempts. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs9596440 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9596440 come from?

GWAS Catalog, Molecular psychiatry 2022, PMID:35347246. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Suicide attempts (rs9596440). MyGeneLog™. https://www.mygenelog.com/variants/rs9596440

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