Sensitive

Peripheral artery disease

IPO5 · rs9584669

Where this position leads

Condition: Peripheral Artery Disease

rs9584669 Condition: Peripheral Artery Disease Peripheral Artery Disease Condition rs9584669 rs9584669 IPO5

What the study found

Who was studied 785 Japanese ancestry cases, 3,383 Japanese ancestry controls; replicated in 2,379 Japanese ancestry cases, 16,752 Japanese ancestry controls.

The effect Each copy of the C allele carried 1.72 times the odds of Peripheral artery disease (95% confidence interval 1.52-2.00); p = 7 × 10−14.

Where it sits Chromosome 13, band 13q32.2 — between genes, 0.2 kb from LOC105370324.

What each result means

C/C Two copies of the version the research linked to Peripheral artery disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Peripheral artery disease. That is a smaller link than two copies.
T/T No copy of the version the research linked to Peripheral artery disease. This is the starting point the study compared everyone against.
Source

Questions about rs9584669

What is rs9584669?

rs9584669 is a single position in the genome, in or near the IPO5 gene. Published research associates it with peripheral artery disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9584669 linked to?

On MyGeneLog this position is linked to Peripheral Artery Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs9584669 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9584669 come from?

GWAS Catalog, PLoS One 2015, PMID:26488411. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Peripheral artery disease (rs9584669). MyGeneLog™. https://www.mygenelog.com/variants/rs9584669

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