Standard

Morning vs. evening chronotype

FBXL3 · rs9565309

Where this position leads

Condition: Sleep and Circadian Rhythm

rs9565309 Condition: Sleep and Circadian Rhythm Sleep and Circadian Rhythm Condition rs9565309 rs9565309 FBXL3

What the study found

Who was studied 38,937 European ancestry morning chronotype individuals, 50,346 European ancestry evening chronotype individuals.

The effect Each copy of the T allele carried 1.19 times the odds of Morning vs. evening chronotype (95% confidence interval 1.12-1.26); p = 4 × 10−8.

How common The T allele had a frequency of about 97% in the people studied.

Where it sits Chromosome 13, band 13q22.3 — in the 3′ untranslated region of CLN5.

What each result means

C/C No copy of the version the research linked to Morning vs. evening chronotype. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Morning vs. evening chronotype. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Morning vs. evening chronotype. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs9565309

What is rs9565309?

rs9565309 is a single position in the genome, in or near the FBXL3 gene. Published research associates it with morning vs. evening chronotype. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9565309 linked to?

On MyGeneLog this position is linked to Sleep and Circadian Rhythm. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs9565309?

Subjects that appear in the title or abstract of the same papers as this rsID include sleep and insomnia (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs9565309 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9565309 come from?

GWAS Catalog, Nat Commun 2016, PMID:26835600. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Morning vs. evening chronotype (rs9565309). MyGeneLog™. https://www.mygenelog.com/variants/rs9565309

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