Sensitive

Type 2 diabetes

SGCG · rs9552911

Where this position leads

Condition: Type 2 Diabetes

rs9552911 Condition: Type 2 Diabetes Type 2 Diabetes Condition rs9552911 rs9552911 SGCG

What the study found

Who was studied 842 Punjabi Sikh ancestry cases, 774 Punjabi Sikh ancestry controls; replicated in up to 2,512 Punjabi Sikh ancestry cases and 3,201 Punjabi Sikh ancestry controls, up to 16,128 South Asian ancestry cases and 23,846 South Asian ancestry controls, up to 16,746 East Asian ancestry cases and 16,961 East Asian ancestry controls, up to 8,130 European ancestry cases and 38,987 European ancestry controls.

The effect Each copy of the G allele carried 1.49 times the odds of Type 2 diabetes (95% confidence interval 1.30-1.72); p = 2 × 10−8.

How common The G allele had a frequency of about 93% in the people studied.

Where it sits Chromosome 13, band 13q12.12 — in an intron of SACS.

What each result means

A/A No copy of the version the research linked to Type 2 diabetes. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Type 2 diabetes. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Type 2 diabetes. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs9552911

What is rs9552911?

rs9552911 is a single position in the genome, in or near the SGCG gene. Published research associates it with type 2 diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9552911 linked to?

On MyGeneLog this position is linked to Type 2 Diabetes. The research behind each link, and its sources, are set out on that condition page.

Does having rs9552911 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9552911 come from?

GWAS Catalog, Diabetes 2013, PMID:23300278. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Type 2 diabetes (rs9552911). MyGeneLog™. https://www.mygenelog.com/variants/rs9552911

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