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Thigh slabs internal fat to muscle ratio

near HNRNPA1P31 · rs9545468

What the study found

Who was studied 37,589 British ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.05 higher (95% confidence interval 0.03-0.07); p = 2 × 10−11.

How common The A allele had a frequency of about 34% in the people studied.

Where it sits Chromosome 13, band 13q31.1 — between genes, 70.4 kb from HNRNPA1P31.

What each result means

A/A Two copies of the version the research linked to Thigh slabs internal fat to muscle ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Thigh slabs internal fat to muscle ratio. That is a smaller link than two copies.
G/G No copy of the version the research linked to Thigh slabs internal fat to muscle ratio. This is the starting point the study compared everyone against.
Source

Questions about rs9545468

What is rs9545468?

rs9545468 is a single position in the genome, in or near the near HNRNPA1P31 gene. Published research associates it with thigh slabs internal fat to muscle ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs9545468 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9545468 come from?

GWAS Catalog, Journal of obesity 2025, PMID:40922984. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Thigh slabs internal fat to muscle ratio (rs9545468). MyGeneLog™. https://www.mygenelog.com/variants/rs9545468

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