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Cardiac MRI latent phenotype (Z53_S1)

DLEU1 · rs9535455

What the study found

Who was studied 47,740 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0434 lower (95% confidence interval 0.029-0.057); p = 2 × 10−9.

Where it sits Chromosome 13, band 13q14.3 — in an intron of DLEU1.

What each result means

A/A Two copies of the version the research linked to Cardiac MRI latent phenotype (Z53_S1). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Cardiac MRI latent phenotype (Z53_S1). That is a smaller link than two copies.
G/G No copy of the version the research linked to Cardiac MRI latent phenotype (Z53_S1). This is the starting point the study compared everyone against.
Source

Questions about rs9535455

What is rs9535455?

rs9535455 is a single position in the genome, in or near the DLEU1 gene. Published research associates it with cardiac mri latent phenotype (z53_s1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs9535455 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9535455 come from?

GWAS Catalog, Nature communications 2026, PMID:42373625. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Cardiac MRI latent phenotype (Z53_S1) (rs9535455). MyGeneLog™. https://www.mygenelog.com/variants/rs9535455

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