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Asthma

CASC15 · rs952579

Where this position leads

Condition: Asthma

rs952579 Condition: Asthma Asthma Condition rs952579 rs952579 CASC15

What the study found

Who was studied 64,538 European ancestry cases, 239,321 European ancestry controls.

The effect Each copy of the A allele carried 1.05 times the odds of Asthma (95% confidence interval 1.03506473248894-1.07053747171829); p = 2 × 10−9.

How common The A allele had a frequency of about 14% in the people studied.

Where it sits Chromosome 6, band 6p22.3 — in an intron of CASC15.

What each result means

A/A Two copies of the version the research linked to Asthma. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Asthma. That is a smaller link than two copies.
G/G No copy of the version the research linked to Asthma. This is the starting point the study compared everyone against.
Source

Questions about rs952579

What is rs952579?

rs952579 is a single position in the genome, in or near the CASC15 gene. Published research associates it with asthma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs952579 linked to?

On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.

Does having rs952579 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs952579 come from?

GWAS Catalog, Nat Commun 2020, PMID:32296059. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Asthma (rs952579). MyGeneLog™. https://www.mygenelog.com/variants/rs952579

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