Triglycerides to Total Lipids in Very Large HDL percentage
ZNF655 · rs952319
0 20152210Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot5Amazon2Apple2China (ByteDance, Huawei, Baidu…)0Others10Total20Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Its strongest genetic-study result is p = 10−68, with 4 associations in the GWAS Catalog.
How this is scored
4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10−50. 2: ClinVar from one lab (1 star), or p ≤ 10−20. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10−8). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.
What the study found
Who was studied 434,646 British ancestry individuals, 8,796 British Central/South Asian individuals, 6,573 British African individuals.
The effect
Each copy of the T allele shifted the measure 0.02 % lower (95% confidence interval 0.02-0.02); p = 4 × 10−11.
Where it sits Chromosome 7, band 7q22.1 — in the 3′ untranslated region of ZNF655.
What each result means
C/CNo copy of the version the research linked to Triglycerides to Total Lipids in Very Large HDL percentage. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Triglycerides to Total Lipids in Very Large HDL percentage. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Triglycerides to Total Lipids in Very Large HDL percentage. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2025 · PMID 41044249 · open access
Questions about rs952319
What is rs952319?
rs952319 is a single position in the genome, in or near the ZNF655 gene. Published research associates it with triglycerides to total lipids in very large hdl percentage. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs952319 linked to?
On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.
Does having rs952319 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs952319 come from?
GWAS Catalog, Nature genetics 2025, PMID:41044249. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 20152210Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot5Amazon2Apple2China (ByteDance, Huawei, Baidu…)0Others10Total20Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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Triglycerides to Total Lipids in Very Large HDL percentage (rs952319). MyGeneLog™. https://www.mygenelog.com/variants/rs952319