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C-reactive protein

LINC00676 · rs9521492

Where this position leads

Condition: C-Reactive Protein Levels

rs9521492 Condition: C-Reactive Protein Levels C-Reactive Protein Levels Condition rs9521492 rs9521492 LINC00676

What the study found

Who was studied 353,466 European ancestry individuals, 83,025 East Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0131 lower (95% confidence interval 0.0088-0.0174); p = 5 × 10−9.

Where it sits Chromosome 13, band 13q34 — in an intron of LINC00676.

What each result means

A/A No copy of the version the research linked to C-reactive protein. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to C-reactive protein. That is a smaller link than two copies.
G/G Two copies of the version the research linked to C-reactive protein. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs9521492

What is rs9521492?

rs9521492 is a single position in the genome, in or near the LINC00676 gene. Published research associates it with c-reactive protein. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9521492 linked to?

On MyGeneLog this position is linked to C-Reactive Protein Levels. The research behind each link, and its sources, are set out on that condition page.

Does having rs9521492 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9521492 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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C-reactive protein (rs9521492). MyGeneLog™. https://www.mygenelog.com/variants/rs9521492

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