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GPA33 protein levels

near SLC10A2 · rs9514085

Where this position leads

Condition: Celiac Disease

rs9514085 Condition: Celiac Disease Celiac Disease Condition rs9514085 rs9514085 near SLC10A2

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0493 higher (95% confidence interval 0.034-0.064); p = 1 × 10−11.

How common The G allele had a frequency of about 15% in the people studied.

Where it sits Chromosome 13, band 13q33.1 — between genes, 9.6 kb from SLC10A2.

What each result means

C/C No copy of the version the research linked to GPA33 protein levels. This is the starting point the study compared everyone against.
C/G One copy of the version the research linked to GPA33 protein levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to GPA33 protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs9514085

What is rs9514085?

rs9514085 is a single position in the genome, in or near the near SLC10A2 gene. Published research associates it with gpa33 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9514085 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs9514085 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9514085 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

GPA33 protein levels (rs9514085). MyGeneLog™. https://www.mygenelog.com/variants/rs9514085

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