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Waist-to-hip ratio adjusted for BMI

HCG27 · rs9501520

What the study found

Who was studied 186,825 British ancestry men.

The effect Each copy of the C allele shifted the measure 0.02 higher (95% confidence interval 0.014-0.026); p = 2 × 10−10.

Where it sits Chromosome 6, band 6p21.33 — in an intron of HCG27.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Waist-to-hip ratio adjusted for BMI compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Waist-to-hip ratio adjusted for BMI.
T/T Published research associates this genotype with typical/baseline likelihood of Waist-to-hip ratio adjusted for BMI — no copies of the reported risk allele.
Source

Questions about rs9501520

What is rs9501520?

rs9501520 is a single position in the genome, in or near the HCG27 gene. Published research associates it with waist-to-hip ratio adjusted for bmi. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs9501520 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9501520 come from?

GWAS Catalog, Scientific reports 2021, PMID:34021172. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Waist-to-hip ratio adjusted for BMI (rs9501520). MyGeneLog™. https://www.mygenelog.com/variants/rs9501520

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