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Mean corpuscular volume (UKB data field 30040)

OR5M7P · rs949359

Where this position leads

Condition: Celiac Disease

rs949359 Condition: Celiac Disease Celiac Disease Condition rs949359 rs949359 OR5M7P

What the study found

Who was studied 394,642 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0185 lower (95% confidence interval 0.013-0.024); p = 1 × 10−11.

How common The G allele had a frequency of about 12% in the people studied.

Where it sits Chromosome 11, band 11q12.1 — in a non-coding transcript of OR5M7P.

What each result means

A/A No copy of the version the research linked to Mean corpuscular volume (UKB data field 30040). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Mean corpuscular volume (UKB data field 30040). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Mean corpuscular volume (UKB data field 30040). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs949359

What is rs949359?

rs949359 is a single position in the genome, in or near the OR5M7P gene. Published research associates it with mean corpuscular volume (ukb data field 30040). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs949359 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs949359 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs949359 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Mean corpuscular volume (UKB data field 30040) (rs949359). MyGeneLog™. https://www.mygenelog.com/variants/rs949359

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