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Adult body size

RNF144B · rs9477762

What the study found

Who was studied 453,169 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0202 lower (95% confidence interval 0.014-0.026); p = 4 × 10−11.

How common The A allele had a frequency of about 95% in the people studied.

Where it sits Chromosome 6, band 6p22.3 — between genes, 13.6 kb from MIR548A1HG.

What each result means

A/A Two copies of the version the research linked to Adult body size. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Adult body size. That is a smaller link than two copies.
T/T No copy of the version the research linked to Adult body size. This is the starting point the study compared everyone against.
Source

Questions about rs9477762

What is rs9477762?

rs9477762 is a single position in the genome, in or near the RNF144B gene. Published research associates it with adult body size. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs9477762 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9477762 come from?

GWAS Catalog, BMJ (Clinical research ed.) 2020, PMID:32376654. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Adult body size (rs9477762). MyGeneLog™. https://www.mygenelog.com/variants/rs9477762

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