Sensitive

Kidney stone disease

LINC02537 · rs9472142

Where this position leads

Condition: Urolithiasis

rs9472142 Condition: Urolithiasis Urolithiasis Condition rs9472142 rs9472142 LINC02537

What the study found

Who was studied 17,101 European ancestry cases, 721,947 European ancestry controls.

The effect Each copy of the T allele carried 1.08 times the odds of Kidney stone disease (95% confidence interval 1.05-1.1); p = 4 × 10−10.

How common The T allele had a frequency of about 31% in the people studied.

Where it sits Chromosome 6, band 6p21.1 — in an intron of LINC02537.

What each result means

C/C No copy of the version the research linked to Kidney stone disease. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Kidney stone disease. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Kidney stone disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs9472142

What is rs9472142?

rs9472142 is a single position in the genome, in or near the LINC02537 gene. Published research associates it with kidney stone disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9472142 linked to?

On MyGeneLog this position is linked to Urolithiasis. The research behind each link, and its sources, are set out on that condition page.

Does having rs9472142 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9472142 come from?

GWAS Catalog, Journal of the American Society of Nephrology : JASN 2023, PMID:37787550. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Kidney stone disease (rs9472142). MyGeneLog™. https://www.mygenelog.com/variants/rs9472142

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