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Thyroid hormone levels

VEGFA · rs9472138

Where this position leads

Condition: Thyroid Stimulating Hormone (TSH) Levels

rs9472138 Condition: Thyroid Stimulating Hormone (TSH) Levels Thyroid Stimulating Hormone (TSH) Levels Condition Topic: Blood sugar and insulin Blood sugar and insulin Topic rs9472138 rs9472138 VEGFA

Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.

What the study found

Who was studied up to 14,459 European ancestry females, up to 10,936 European ancestry males, up to 433 Old Order Amish females, up to 592 Old Order Amish males.

The effect Each copy of the T allele shifted the measure 0.065 lower (95% confidence interval 0.038-0.092); p = 5 × 10−6.

How common The T allele had a frequency of about 28% in the people studied.

Where it sits Chromosome 6, band 6p21.1 — in an intron of LOC105375070.

What each result means

C/C No copy of the version the research linked to Thyroid hormone levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Thyroid hormone levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Thyroid hormone levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs9472138

What is rs9472138?

rs9472138 is a single position in the genome, in or near the VEGFA gene. Published research associates it with thyroid hormone levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9472138 linked to?

On MyGeneLog this position is linked to Thyroid Stimulating Hormone (TSH) Levels. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs9472138?

Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (8 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs9472138 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9472138 come from?

GWAS Catalog, PLoS Genet 2013, PMID:23408906. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Thyroid hormone levels (rs9472138). MyGeneLog™. https://www.mygenelog.com/variants/rs9472138

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