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Who was studied 5,999 East Asian ancestry cases, 9,001 East Asian ancestry controls, 794 Malay ancestry cases, 1,240 Malay ancestry controls, 159 Filipino ancestry cases, 1,624 Filipino ancestry controls; replicated in 18,127 East Asian ancestry cases, 17,746 East Asian ancestry controls.
The effect
Each copy of the C allele carried 1.12 times the odds of Type 2 diabetes (95% confidence interval 1.08-1.16); p = 2 × 10−10.
How common The C allele had a frequency of about 27% in the people studied.
Where it sits Chromosome 6, band 6p21.2 — in an intron of ZFAND3.
What each result means
C/CTwo copies of the version the research linked to Type 2 diabetes. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Type 2 diabetes. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Type 2 diabetes. This is the starting point the study compared everyone against.
rs9470794 is a single position in the genome, in or near the ZFAND3 gene. Published research associates it with type 2 diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs9470794 linked to?
On MyGeneLog this position is linked to Type 2 Diabetes. The research behind each link, and its sources, are set out on that condition page.
Does having rs9470794 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs9470794 come from?
GWAS Catalog, Nature genetics 2011, PMID:22158537. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Type 2 diabetes (rs9470794). MyGeneLog™. https://www.mygenelog.com/variants/rs9470794