C/CPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Drug-induced Stevens-Johnson syndrome or toxic epidermal necrolysis (SJS/TEN) compared to the general population. (GWAS Catalog, Orphanet J Rare Dis 2011, PMID:21801394)
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Drug-induced Stevens-Johnson syndrome or toxic epidermal necrolysis (SJS/TEN). (GWAS Catalog, Orphanet J Rare Dis 2011, PMID:21801394)
T/TPublished research associates this genotype with typical/baseline likelihood of Drug-induced Stevens-Johnson syndrome or toxic epidermal necrolysis (SJS/TEN) — no copies of the reported risk allele. (GWAS Catalog, Orphanet J Rare Dis 2011, PMID:21801394)
rs9469003 is a single position in the genome, in or near the HCP5 gene. Published research associates it with drug-induced stevens-johnson syndrome or toxic epidermal necrolysis (sjs/ten). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs9469003 linked to?
On MyGeneLog this position is linked to Drug-Induced Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis. The research behind each link, and its sources, are set out on that condition page.
Does having rs9469003 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs9469003 come from?
GWAS Catalog, Orphanet J Rare Dis 2011, PMID:21801394. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.