Drug-induced Stevens-Johnson syndrome or toxic epidermal necrolysis (SJS/TEN)
HCP5 · rs9469003
0 465218223320Reads by AI crawlersClaude5ChatGPT2Google · Gemini0Perplexity1Meta AI8Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)3ByteDance (Doubao)3Others20Total46Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 424 European ancestry cases, 1,881 European ancestry controls.
The effect
Each copy of the C allele carried 1.73 times the odds of Drug-induced Stevens-Johnson syndrome or toxic epidermal necrolysis (SJS/TEN) (95% confidence interval 1.44-2.08); p = 2 × 10−9.
How common The C allele had a frequency of about 15% in the people studied.
Where it sits Chromosome 6, band 6p21.33 — between genes, 1.6 kb from LINC01149.
What each result means
C/CTwo copies of the version the research linked to Drug-induced Stevens-Johnson syndrome or toxic epidermal necrolysis (SJS/TEN). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Drug-induced Stevens-Johnson syndrome or toxic epidermal necrolysis (SJS/TEN). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Drug-induced Stevens-Johnson syndrome or toxic epidermal necrolysis (SJS/TEN). This is the starting point the study compared everyone against.
Orphanet journal of rare diseases · 2011 · PMID 21801394 · open access
Questions about rs9469003
What is rs9469003?
rs9469003 is a single position in the genome, in or near the HCP5 gene. Published research associates it with drug-induced stevens-johnson syndrome or toxic epidermal necrolysis (sjs/ten). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs9469003 linked to?
On MyGeneLog this position is linked to Drug-Induced Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis. The research behind each link, and its sources, are set out on that condition page.
Does having rs9469003 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs9469003 come from?
GWAS Catalog, Orphanet J Rare Dis 2011, PMID:21801394. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 465218223320Reads by AI crawlersClaude5ChatGPT2Google · Gemini0Perplexity1Meta AI8Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)3ByteDance (Doubao)3Others20Total46Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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