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Liver enzyme levels

GPLD1 · rs9467160

What the study found

Who was studied 7,751 European ancestry individuals; replicated in 1,005 European ancestry individuals, 3,669 Asian Indian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.03 U/L higher (95% confidence interval 0.024-0.044); p = 1 × 10−11.

How common The A allele had a frequency of about 24% in the people studied.

Where it sits Chromosome 6, band 6p22.3 — in an intron of GPLD1.

What each result means

A/A Two copies of the version the research linked to Liver enzyme levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Liver enzyme levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Liver enzyme levels. This is the starting point the study compared everyone against.
Source

Questions about rs9467160

What is rs9467160?

rs9467160 is a single position in the genome, in or near the GPLD1 gene. Published research associates it with liver enzyme levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs9467160 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9467160 come from?

GWAS Catalog, American journal of human genetics 2008, PMID:18940312. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Liver enzyme levels (rs9467160). MyGeneLog™. https://www.mygenelog.com/variants/rs9467160

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