Standard

Urea levels

DCDC2 · rs9467077

Where this position leads

Condition: Gout

rs9467077 Condition: Gout Gout Condition rs9467077 rs9467077 DCDC2

What the study found

Who was studied 342,286 European ancestry individuals, 6,015 African ancestry individuals, 7,336 South Asian ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0185 higher (95% confidence interval 0.013-0.024); p = 6 × 10−10.

Where it sits Chromosome 6, band 6p22.3 — in an intron of DCDC2.

What each result means

C/C Two copies of the version the research linked to Urea levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Urea levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Urea levels. This is the starting point the study compared everyone against.
Source

Questions about rs9467077

What is rs9467077?

rs9467077 is a single position in the genome, in or near the DCDC2 gene. Published research associates it with urea levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9467077 linked to?

On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.

Does having rs9467077 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9467077 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Urea levels (rs9467077). MyGeneLog™. https://www.mygenelog.com/variants/rs9467077

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