Standard

Creatinine levels

E2F3 · rs9465741

Where this position leads

Condition: Kidney Function

rs9465741 Condition: Kidney Function Kidney Function Condition rs9465741 rs9465741 E2F3

What the study found

Who was studied 507,850 East Asian ancestry individuals, 420,829 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0123 lower (95% confidence interval 0.0098-0.0148); p = 9 × 10−20.

Where it sits Chromosome 6, band 6p22.3 — in an intron of E2F3.

What each result means

A/A Two copies of the version the research linked to Creatinine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Creatinine levels. That is a smaller link than two copies.
C/C No copy of the version the research linked to Creatinine levels. This is the starting point the study compared everyone against.
Source

Questions about rs9465741

What is rs9465741?

rs9465741 is a single position in the genome, in or near the E2F3 gene. Published research associates it with creatinine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9465741 linked to?

On MyGeneLog this position is linked to Kidney Function. The research behind each link, and its sources, are set out on that condition page.

Does having rs9465741 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9465741 come from?

GWAS Catalog, Nature communications 2025, PMID:40436827. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Creatinine levels (rs9465741). MyGeneLog™. https://www.mygenelog.com/variants/rs9465741

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