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Cholesteryl ester levels in HDL

SMIM29-AS1 · rs9461976

What the study found

Who was studied 115,082 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0781 higher (95% confidence interval 0.054-0.102); p = 3 × 10−10.

How common The G allele had a frequency of about 97% in the people studied.

Where it sits Chromosome 6, band 6p21.31 — in an intron of SMIM29-AS1.

What each result means

A/A No copy of the version the research linked to Cholesteryl ester levels in HDL. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Cholesteryl ester levels in HDL. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Cholesteryl ester levels in HDL. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs9461976

What is rs9461976?

rs9461976 is a single position in the genome, in or near the SMIM29-AS1 gene. Published research associates it with cholesteryl ester levels in hdl. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs9461976 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9461976 come from?

GWAS Catalog, PLoS biology 2022, PMID:35213538. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Cholesteryl ester levels in HDL (rs9461976). MyGeneLog™. https://www.mygenelog.com/variants/rs9461976

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