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Sex hormone-binding globulin levels

near HLA-DQB1 · rs9461793

What the study found

Who was studied 196,901 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0267 lower (95% confidence interval 0.02-0.034); p = 1 × 10−13.

How common The C allele had a frequency of about 28% in the people studied.

Where it sits Chromosome 6, band 6p21.32 — between genes, 0.4 kb from HLA-DQB1.

What each result means

A/A No copy of the version the research linked to Sex hormone-binding globulin levels. This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Sex hormone-binding globulin levels. That is a smaller link than two copies.
C/C Two copies of the version the research linked to Sex hormone-binding globulin levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs9461793

What is rs9461793?

rs9461793 is a single position in the genome, in or near the near HLA-DQB1 gene. Published research associates it with sex hormone-binding globulin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs9461793 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9461793 come from?

GWAS Catalog, Endocrinology 2022, PMID:35192695. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Sex hormone-binding globulin levels (rs9461793). MyGeneLog™. https://www.mygenelog.com/variants/rs9461793

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