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Psoriasis

near VN1R10P · rs9461363

Where this position leads

Condition: Psoriasis

rs9461363 Condition: Psoriasis Psoriasis Condition rs9461363 rs9461363 near VN1R10P

What the study found

Who was studied 26,279 European ancestry cases, 442,230 European ancestry controls, 2,590 South Asian ancestry cases, 1,720 South Asian ancestry controls.

The effect Each copy of the A allele shifted the measure 0.106 higher (95% confidence interval 0.069-0.143); p = 2 × 10−20.

Where it sits Chromosome 6, band 6p22.1 — between genes, 14.6 kb from VN1R10P.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Psoriasis compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Psoriasis.
G/G Published research associates this genotype with typical/baseline likelihood of Psoriasis — no copies of the reported risk allele.
Source

Questions about rs9461363

What is rs9461363?

rs9461363 is a single position in the genome, in or near the near VN1R10P gene. Published research associates it with psoriasis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9461363 linked to?

On MyGeneLog this position is linked to Psoriasis. The research behind each link, and its sources, are set out on that condition page.

Does having rs9461363 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9461363 come from?

GWAS Catalog, Journal of translational medicine 2025, PMID:39885523. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Psoriasis (rs9461363). MyGeneLog™. https://www.mygenelog.com/variants/rs9461363

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