Triglyceride percentage of total lipids in intermediate-density lipoprotein
IGF2R · rs9457827
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 199,732 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.0792 lower (95% confidence interval 0.055-0.103); p = 7 × 10−11.
How common The T allele had a frequency of about 2% in the people studied.
Where it sits Chromosome 6, band 6q25.3 — in an intron of IGF2R.
What each result means
C/CNo copy of the version the research linked to Triglyceride percentage of total lipids in intermediate-density lipoprotein. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Triglyceride percentage of total lipids in intermediate-density lipoprotein. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Triglyceride percentage of total lipids in intermediate-density lipoprotein. That is the strongest link of the three results. A link in a study is not a diagnosis.
British journal of cancer · 2025 · PMID 40307439 · open access
Questions about rs9457827
What is rs9457827?
rs9457827 is a single position in the genome, in or near the IGF2R gene. Published research associates it with triglyceride percentage of total lipids in intermediate-density lipoprotein. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs9457827 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs9457827 come from?
GWAS Catalog, British journal of cancer 2025, PMID:40307439. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Triglyceride percentage of total lipids in intermediate-density lipoprotein (rs9457827). MyGeneLog™. https://www.mygenelog.com/variants/rs9457827