Standard

Male-pattern baldness

near RUNX3 · rs9438874

Where this position leads

Condition: Androgenetic Alopecia (Male Pattern Baldness)

rs9438874 Condition: Androgenetic Alopecia (Male Pattern Baldness) Androgenetic Alopecia (Male Pattern… Condition rs9438874 rs9438874 near RUNX3

What the study found

Who was studied 205,327 European ancestry males.

The effect Each copy of the A allele shifted the measure 0.047 higher (95% confidence interval 0.037-0.057); p = 8 × 10−19.

How common The A allele had a frequency of about 9% in the people studied.

Where it sits Chromosome 1, band 1p36.11 — between genes, 3.1 kb from RUNX3.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Male-pattern baldness compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Male-pattern baldness.
G/G Published research associates this genotype with typical/baseline likelihood of Male-pattern baldness — no copies of the reported risk allele.
Source

Questions about rs9438874

What is rs9438874?

rs9438874 is a single position in the genome, in or near the near RUNX3 gene. Published research associates it with male-pattern baldness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9438874 linked to?

On MyGeneLog this position is linked to Androgenetic Alopecia (Male Pattern Baldness). The research behind each link, and its sources, are set out on that condition page.

Does having rs9438874 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9438874 come from?

GWAS Catalog, Nat Commun 2018, PMID:30573740. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Male-pattern baldness (rs9438874). MyGeneLog™. https://www.mygenelog.com/variants/rs9438874

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